Camp JG*, Sekine K*, Gerber T, Loeffler-Wirth H, Binder H, Gac M, Kanton S, Kageyama J, Damm G, Seehofer D, Belicova L, Bickle M, Barsacchi R, Okuda R, Yoshizawa E, Kimura M, Ayabe H, Taniguchi H, Takebe T*, Treutlein B*. Multilineage communication regulates human liver bud development from pluripotency. Nature 546, 533-538 (2017).


J.G. Camp, B. Treutlein. Human development: Advances in mini-brain technology, Nature, 545, 39–40 (2017).


J.G. Camp*, B. Treutlein*. Human Organomics: A fresh approach to studying human development using single-cell transcriptomics. Development 2017 144: 1584-1587; doi: 10.1242/dev.150458.  *Equal contribution


T. Gerber*, E. Willscher*, H. Loeffler-Wirth, L. Hopp, D. Schadendorf, M. Schartl, U. Anderegg, G. Camp, B. Treutlein*, H. Binder* and M. Kunz*, Mapping heterogeneity in patient-derived melanoma cultures by single-cell RNA-seq. Oncotarget, doi: 10.18632/oncotarget.13666 (2016).


F. Mora-Bermúdez*, F. Badsha*, S. Kanton*, J.G. Camp*, B. Vernot, K. Köhler, B. Voigt, K. Okita, T. Maricic, Z. He, R. Lachmann, S. Pääbo*, B. Treutlein* and W.B. Huttner*. Differences and similarities between human and chimpanzee neural progenitors during cerebral cortex development.
eLife 5, doi:10.7554/eLife.18683 (2016).


B. Treutlein*, Q.Y. Lee*, J.G. Camp, M. Mall, W. Koh, S.A.M. Shariati, S. Sim, N.F. Neff, J.M. Skotheim, M. Wernig*, S. Quake*. Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq.
Nature534, 391-395 (2016).

News and Views by Bruno Di Stefano & Konrad Hochedlinger


J. G. Camp*, F. Badsha*, M. Florio, S. Kanton, T. Gerber, M. Wilsch-Brauninger, E. Lewitus, A. Sykes, W. Hevers, M. Lancaster, J. A. Knoblich, R. Lachmann, S. Paabo*, W. B. Huttner*, B. Treutlein*.
Human cerebral organoids recapitulate gene expression programs of fetal neocortex development.
PNAS 112(51): 15672-15677 (2015).


A.E. Vaughan, A.N. Brumwell, Y. Xi, J.E. Gotts, D.G. Brownfield, B. Treutlein, K. Tan,
V. Tan, F.C. Liu, M.R. Looney, M.A. Matthay, J.R. Rock, H.A. Chapman,
Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury.
Nature, 517, 621-625 (2015).


B. Treutlein*, O. Gokce*, S. R. Quake* and T. C. Südhof*,
Cartography of Neurexins mapped by single-molecule long-read mRNA sequencing. 
PNAS, 111 (13), 1291-99 (2014).

Press: Stanford News


B. Treutlein*, D. G. Brownfield*, A. R. Wu, N. F. Neff, G. L. Mantalas, F. H. Espinoza, T. J. Desai*, M. A. Krasnow* and S. R. Quake*,
Reconstructing lineage hierarchies of the distal lung epithelium using single cell RNA-seq. 
Nature, 509, 371-375 (2014).

Press: Science Daily 


A. R. Wu, N. F. Neff, T. Kalisky, P. Dalerba, B. Treutlein, M. E. Rothenberg, F. M. Mburu, G. L. Mantalas, S. Sim, M. F. Clarke* and S. R. Quake*,
Quantitative assessment of single-cell RNA-sequencing methods.
Nature Methods, 11, 41-46 (2013).


B. Treutlein and J. Michaelis,
Single molecule studies of RNA polymerases.
Chem. Rev., 113, 8377-99 (2013).


B. Treutlein, A. Muschielok, J. Andrecka, A. Jawhari, C. Buchen, D. Kostrewa, F. Hög, P. Cramer* and J. Michaelis*,
Dynamic architecture of a minimal RNA Polymerase II open promoter complex.
Molecular Cell, 46, 136-146 (2012).


B. Treutlein and J. Michaelis,
Direct Observation of Single RNA Polymerase Processing through a Single Endogenous Gene in a Living Yeast Cell.
Angew Chem Int Ed, 50, 9788-9790 (2011).


J. Andrecka, B. Treutlein, M. I. Arcusa, A. Muschielok, R. Lewis, 
A. C. M. Cheung, P. Cramer* and J. Michaelis*,
Nano-positioning system reveals the course of upstream and nontemplate DNA within the RNA polymerase II elongation complex. 
Nucleic Acids Research, 37, 5803-5809 (2009).


J.A. Huffman*, B. Treutlein* and U. Pöschl,
Fluorescent biological aerosol particle concentrations and size distributions measured with an ultraviolet aerodynamic particle sizer (UV-APS) in Central Europe. 
Atmospheric Chemistry and Physics 10 (7), 3215 (2010).


S. Schuy, B. Treutlein, A. Pietuch and A. Janshoff,
In situ synthesis of lipopeptides as versatile receptors for the specific binding of nanoparticles and liposomes to solid-supported membranes.
Small 4 (7), 970 (2008).